Felice Mastroleo

Research output

Research output per year 2005 2009 2012 2021 2022 2023 2024 2025

• 34 Article
• 5 Chapter
• 2 Literature review
• 2 Doctoral thesis
• 9 More
  • 2 Master's thesis
  • 2 Professional Bachelor's thesis
  • 1 Book of abstracts
  • 1 Third partyreport
  • 1 ER - External report
  • 1 In-proceedings paper
  • 1 Special issue

Research output per year

Research output per year

Search results

• 2025

  ARTHROSPIRA-C space flight experiment: Validation of biomass and oxygen production bioprocesses in a space bioreactor prior to upload to space

  Fahrion, J., Renaud, C., Coninx, I., Heylen, W., Mastroleo, F., Gupta, S., Bayon-Vicente, G., Wattiez, R., Leys, N. & Dussap, C.-G., Apr 2025, In: Acta Astronautica. 229, p. 374-390 17 p.

  Research output › peer-review

  Open Access

• Chronic low-dose rate irradiation induces transient hormesis effect on cyanobacterium Limnospira indica

  Fahrion, J., Gupta, S., Mastroleo, F., Dussap, C.-G. & Leys, N., 21 Mar 2025, In: iScience. 28, 3, 111891.

  Research output › peer-review

  Open Access
• 2024

  Development and implementation of a simulated microgravity setup for edible cyanobacteria

  Ellena, G., Fahrion, J., Gupta, S., Dussap, C.-G., Mazzoli, A., Leys, N. & Mastroleo, F., Dec 2024, In: npj Microgravity. 10, 1, 14 p., 99.

  Research output › peer-review

  Open Access

• Radiotolerance of N-cycle bacteria and their transcriptomic response to low-dose space-analogue ionizing irradiation

  Verbeelen, T., Fernandez, C. A., Nguyen, T. H., Gupta, S., Leroy, B., Wattiez, R., Vlaeminck, S. E., Leys, N., Ganigué, R. & Mastroleo, F., May 2024, In: iScience. 27, 5, 19 p., 109596.

  Research output › peer-review

  Open Access

• The genus Limnospira contains only two species both unable to produce microcystins: L. maxima and L. platensis comb. nov.

  Pinchart, P.-E., Marter, P., Brinkmann, H., Quilichini, Y., Ahmed, M. M., Petersen, J., Pasqualini, V. & Mastroleo, F., 20 Sep 2024, In: iScience. 27, 9, 17 p., 110845.

  Research output › peer-review

  Open Access

• Viromic and Metagenomic Analyses of Commercial Spirulina Fermentations Reveal Remarkable Microbial Diversity

  McDonnell, B., Parlindungan, E., Vasiliauskaite, E., Bottacini, F., Coughlan, K., Krishnaswami, L. P., Sassen, T., Lugli, G. A., Ventura, M., Mastroleo, F., Mahony, J. & van Sinderen, D., Jul 2024, In: Viruses. 16, 7, 14 p., 1039.

  Research output › peer-review

  Open Access

• Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity

  Verbeelen, T., Alvarez Hernandez, C., Nguyen, T. H., Gupta, S., Aarts, R., Tabury, K., Leroy, B., Wattiez, R., Vlaeminck, S. E., Leys, N., Ganigué, R. & Mastroleo, F., Dec 2024, In: npj Microgravity. 10, 1, 19 p., 3.

  Research output › peer-review

  Open Access
• 2023

  Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research

  Manzano, A., Weging, S., Bezdan, D., Borg, J., Cahill, T., Carnero-Diaz, E., Cope, H., Deane, C. S., Etheridge, T., Giacomello, S., Hardiman, G., Leys, N., Madrigal, P., Mastroleo, F., Medina, F. J., Mieczkowski, J., Fernandez-Rojo, M. A., Siew, K., Szewczyk, N. J. & Walsh, S. B. & 2 others, Silveira, W. A. D. & Herranz, R., 15 Sep 2023, In: iScience. 26, 9, 107289.

  Research output › peer-review

  Open Access

• Human intestinal organoids and microphysiological systems for modeling radiotoxicity and assessing radioprotective agents

  Bouges, E., Segers, C., Leys, N., Lebeer, S., Zhang, J. & Mastroleo, F., 15 Dec 2023, In: Cancers. 15, 24, 20 p., 5859.

  Research output › peer-review

  Open Access

• Limnospira indica PCC8005 and lacticaseibacillus rhamnosus GG mixed dietary combination reduces pelvic irradiation-induced symptoms in mice

  Gholam, S.-R., Segers, C., Ahmed, M. M., Coolkens, A., Baatout, S., Leys, N. & Mastroleo, F., 11 May 2023, In: Applied Microbiology. 3, 2, p. 448-464 17 p.

  Research output › peer-review

  Open Access

• Limnospira indica PCC 8005 supplementation prevents pelvic irradiation-induced dysbiosis but not acute inflammation in mice

  Segers, C., Ahmed, M. M., Coolkens, A., Wouters, S., Baatout, S., Leys, N., Lebeer, S., Verslegers, M. & Mastroleo, F., Mar 2023, In: Antioxidants. 12, 3, 18 p., 572.

  Research output › peer-review

  Open Access

• Microcystins and Cyanobacterial Contaminants in the French Small-Scale Productions of Spirulina (Limnospira sp.)

  Pinchart, P. E., Leruste, A., Pasqualini, V. & Mastroleo, F., Jun 2023, In: Toxins. 15, 6, 16 p., 354.

  Research output › peer-review

  Open Access

• Plant and microbial science and technology as cornerstones to Bioregenerative Life Support Systems in space

  De Micco, V., Amitrano, C., Mastroleo, F., Aronne, G., Battistelli, A., Carnero-Diaz, E., De Pascale, S., Detrell, G., Dussap, C. G., Ganigué, R., Jakobsen, Ø. M., Poulet, L., Van Houdt, R., Verseux, C., Vlaeminck, S. E., Willaert, R. & Leys, N., Dec 2023, In: npj Microgravity. 9, 1, 12 p., 69.

  Research output › peer-review

  Open Access

• RNA extraction protocol from low-biomass bacterial Nitrosomonas europaea and Nitrobacter winogradskyi cultures for whole transcriptome studies

  Verbeelen, T., Houdt, R. V., Leys, N., Ganigué, R. & Mastroleo, F., 15 Sep 2023, In: STAR Protocols. 4, 3, 9 p., 102358.

  Research output › peer-review

  Open Access
• 2022

  Limnospira indica PCC 8005 or Lacticaseibacillus rhamnosus GG Dietary Supplementation Modulate the Gut Microbiome in Mice

  Segers, C., Ahmed, M., Coolkens, A., Baatout, S., Leys, N., Lebeer, S., Verslegers, M. & Mastroleo, F., 31 Aug 2022, In: Applied Microbiology. 2, 3, p. 636-650 15 p., 1030049.

  Research output › peer-review

  Open Access

  File
  46 Downloads (Pure)

• Metaproteomics, heterotrophic growth, and distribution of nitrosomonas europaea and nitrobacter winogradskyi after long-term operation of an autotrophic nitrifying biofilm reactor

  Mastroleo, F., Arnau, C., Verbeelen, T., Ahmed, M., Gòdia, F., Leys, N. & Van Houdt, R., 9 Mar 2022, In: Applied Microbiology. 2, 1, p. 272-287 16 p., 201002.

  Research output › peer-review

  Open Access

  File
  117 Downloads (Pure)

• Optimization of RNA extraction for bacterial whole transcriptome studies of low-biomass samples

  Verbeelen, T., Van Houdt, R., Leys, N., Ganigué, R. & Mastroleo, F., 9 Oct 2022, (Accepted/In press) In: iScience. 25, p. 1-20 20 p., 105311.

  Research output › peer-review

• Space omics research in Europe - Contributions, geographical distribution and ESA member state funding schemes

  Deane, C. S., Mastroleo, F., Leys, N., da Silveira, W. A. & Herranz, R., 18 Mar 2022, In: iScience. 25, 3, p. 1-18 18 p., 103920.

  Research output › peer-review

  Open Access
• 2021

  Development of Nitrogen Recycling Strategies for Bioregenerative Life Support Systems in Space

  Verbeelen, T., Leys, N., Ganigué, R. & Mastroleo, F., 13 Oct 2021, In: Frontiers in Microbiology. p. 1-17 17 p., 700810.

  Research output › peer-review

  Open Access

• Intestinal mucositis precedes dysbiosis in a mouse model for pelvic irradiation

  Segers, C., Ahmed, M., Claesen, J., Baatout, S., Leys, N., Lebeer, S., Verslegers, M. & Mastroleo, F., 10 Jun 2021, In: ISME Communications. 1, p. 1-10 10 p., 24.

  Research output › peer-review

  Open Access

• Use of Photobioreactors in Regenerative Life Support Systems for Human Space Exploration

  Fahrion, J., Mastroleo, F., Gilles, D. & Leys, N., 29 Jun 2021, In: Frontiers in Microbiology. 12, p. 1-14 14 p., 699525.

  Research output › peer-review

  Open Access

• Why space the opportunity for health and life science innovation: The opportunity for Health and Life Science Innovation

  Davey, M. P., Smith, A., Mehrshahi, P., Harrison, E., Mastroleo, F. & Leys, N., 7 May 2021, UK Space Life and Biomedical Sciences Association. 63 p.

  Research output › peer-review

  Open Access
• 2020

  Growth of Lactobacillus reuteri DSM17938 Under Two Simulated Microgravity Systems: Changes in Reuterin Production, Gastrointestinal Passage Resistance, and Stress Genes Expression Response

  Senatore, G., Mastroleo, F., Leys, N. & Mauriello, G., 1 Jan 2020, In: Astrobiology. 20, 1, p. 1-14 14 p.

  Research output › peer-review

  Open Access

• Limnospira indica PCC8005 growth in photobioreactor: model and simulation of the ISS and ground experiments

  Poughon, L., Laroche, C., Creuly, C., Paillé, C., Lasseur, C., Monsieurs, P., Heylen, W., Coninx, I., Mastroleo, F. & Leys, N., 1 May 2020, In: Life Sciences in Space Research. 25, p. 53-65 13 p.

  Research output › peer-review

  Open Access
• 2019

  Food Supplements to Mitigate Detrimental Effects of Pelvic Radiotherapy

  Segers, C., Verslegers, M., Baatout, S., Leys, N., Lebeer, S. & Mastroleo, F., 3 Apr 2019, In: Microorganisms. 7, 4, p. 1-29 29 p., 97.

  Research output › peer-review

  Open Access

• Reactivation of Microbial Strains and Synthetic Communities After a Spaceflight to the International Space Station: Corroborating the Feasibility of Essential Conversions in the MELiSSA Loop

  Ilgrande, C., Mastroleo, F., Christiaens, M. E. R., Lindeboom, R. E. F., Prat, D., Van Hoey, O., Ambrozova, I., Coninx, I., Heylen, W., Pommerening-Roser, A., Spieck, E., Boon, N., Vlaeminck, S. E., Leys, N. & Clauwaert, P., 4 Jun 2019, In: Astrobiology. 19, 9, 10 p.

  Research output › peer-review

  Open Access
• 2018

  Effect of microgravity & space radiation on microbes

  Senatore, G., Mastroleo, F., Leys, N. & Mauriello, G., 10 May 2018, In: Future Microbiology. 13, 7, p. 831–847 18 p.

  Research output › peer-review

• Quorum sensing in life support systems: The MELiSSA loop

  Condori Catachura, S., Leys, N. & Mastroleo, F., 12 Aug 2018, Quorum Sensing and its Biotechnological Applications. Springer Singapore, p. 249-260 12 p.

  Research output › peer-review

  Open Access
• 2017

  Topical Day | Ionising radiation: how do bacteria cope and what can we learn?

  Janssen, P., Yadav, A., Van Houdt, R., Monsieurs, P., Mastroleo, F., Mijnendonckx, K. & Van Eesbeeck, V., 21 Apr 2017, SCK CEN. (SCK•CEN Reports; no. BA-88)

  Research output › peer-review

• 2016

  Construction and phenotypic characterization of M68, an RruI quorum sensing knockout mutant of the photosynthetic alphaproteobacterium Rhodospirillum rubrum

  Condori Catachura, S., Leys, N. & Mastroleo, F., 16 Mar 2016, In: Microbiology. 167, p. 380-392

  Research output › peer-review

  Open Access
• 2015

  Microbiology Astrobiology

  Mastroleo, F., Leys, N. & Van Houdt, R. (Peer reviewer), 15 Jun 2015, Generation and applications of Extra-terrestrial environments on Earth. 1 ed. Aalborg Ø, Denmark: River publishers, Vol. 1. p. 221-232 (Rivers publishers in standardisation; no. Volume 6).

  Research output › peer-review

• Molecular investigation of radiation resistant cyanobacterium Arthrospira sp. PCC8005

  Badri, H., Janssen, P. (Peer reviewer) & Mastroleo, F. (Peer reviewer), 23 Jan 2015, Mons, Belgium: UMONS - Université de Mons. 291 p.

  Research output

  Open Access

  File
  512 Downloads (Pure)
• 2014

  Caractérisation des souches mutantes de Rhodospirillum rubrum auxquelles il manque des pigments photosynthétiques

  Garufo, S., Condori, S., Coninx, I., Leys, N. (Peer reviewer) & Mastroleo, F., 13 Jun 2014, Liège, Belgium: HEL - Haute Ecole de la Ville de Liège. 108 p.

  Research output

  Open Access

  File
  35 Downloads (Pure)

• Genome Sequences of Cupriavidus metallidurans Strains NA1, NA4, and NE12, Isolated from Space Equipment

  Monsieurs, P., Mijnendonckx, K., Provoost, A., Venkateswaran, K., Ott, M., Leys, N., Van Houdt, R., Moors, H. (Peer reviewer) & Mastroleo, F. (Peer reviewer), 24 Jul 2014, In: Genome Announcements. 2, 4, p. E00719-E00719

  Research output › peer-review

  Open Access

• Photosynthesis at the forefront of a sustainable life

  Janssen, P., Lambreva, M. D., Plumeré, N., Bartolucci, C., Antonacci, A., Buonasera, K., Frese, R. N., Scognamiglio, V., Rea, G., Horemans, N. (Peer reviewer) & Mastroleo, F. (Peer reviewer), Jun 2014, In: Frontiers in Chemistry. 2, p. 1-22

  Research output › peer-review

  Open Access
• 2013

  Modelled microgravity cultivation modulates N-acylhomoserine lactone production in Rhodospirillum rubrum S1H independently of cell density

  Mastroleo, F., Van Houdt, R., Atkison, S., Mergeay, M., Hendrickx, L., Wattiez, R., Leys, N. & Condori Catachura, S. (Peer reviewer), 11 Sep 2013, In: Microbiology. 159, 10, p. 2456-2466

  Research output › peer-review

  Open Access

• Possible scenarios to cultivate cyanobacteria on the Moon for life support

  Schokaert, T. & Mastroleo, F. (Peer reviewer), 26 Aug 2013, Leuven, Belgium: KUL - Katholieke Universiteit Leuven. 93 p.

  Research output

  Open Access

  File
  360 Downloads (Pure)
• 2012

  BIOSMHARS: Biocontamination specific modelling in habitats related to space

  Berthier, A., Leys, N., Van Houdt, R., Tikhomirov, A., Novikova, N., Ilyin, V., Kulmala, I., Lehtimäki, M., Kokkonen, E., Pasanen, P., Abaibou, H. & Mastroleo, F. (Peer reviewer), Jul 2012, Let’s Embrace Space. 1 ed. Luxembourg, Luxembourg: EC - European Commission, Vol. 2. p. 278-284 (Let's Embrace Space; no. volume 2).

  Research output › peer-review

• Differential proteomics and physiology of Pseudomonas putida KT2440 under filament-inducing conditions

  Crabbé, A., Leroy, B., Wattiez, R., Aertsen, A., Leys, N., Cornelis, P., Van Houdt, R. & Mastroleo, F. (Peer reviewer), Nov 2012, In: BMC Microbiology. 12, p. 282-287

  Research output › peer-review

  Open Access

• Monitoring the Microbial Burden in Manned Space Stations

  Van Houdt, R., Leys, N. & Mastroleo, F. (Peer reviewer), Jan 2012, Stress Challenges and Immunity in Space. 1 ed. Heidelberg, Germany: Springer, p. 299-308

  Research output › peer-review

• Ontwikkeling van Illumina data analyse pipeline voor resequencing

  D'Hert, S., Leys, N. (Peer reviewer), Mastroleo, F. (Peer reviewer) & Janssen, P. (Peer reviewer), 11 Jun 2012, Brugge, Belgium: Howest - De Hogeschool West-Vlaanderen. 57 p.

  Research output

  Open Access

  File
  18 Downloads (Pure)

• THESEUS : Towards Human Exploration of Space - a EUropean Strategy

  Worms, J.-C., Walter, N., White, O., Martinez-Schmitt, J., Marshall-Bowman, K., Blanc, S., Monken, I., Hockey, B., Reitz, G., Leys, N., Mastroleo, F., Comet, B., Gerzer, R., Horneck, G. & Baatout, S. (Peer reviewer), Mar 2012, 0 ed. SCK CEN. 200 p. (SCK•CEN Reports; no. ER-1)

  Research output › peer-review

  Open Access

  File
  575 Downloads (Pure)
• 2011

  Gravitational Cell Biology

  Boonstra, J., Bradamante, S., Colige, A. C., Hemmersbach, R., Lambert, C. A., Leys, N., van Loon, J. J. W. A., Nusgens, B. V. & Mastroleo, F. (Peer reviewer), Dec 2011, Laboratory Science with Space Data. 1 ed. Heidelberg, Germany: Springer, Vol. 1. p. 107-112

  Research output › peer-review

• Heavy metal resistance in Cupriavidus metallidurans CH34 is governed by an intricate transcriptional network.

  Monsieurs, P., Moors, H., Van Houdt, R., Janssen, P., Janssen, A., Coninx, I., Mergeay, M., Leys, N. & Mastroleo, F. (Peer reviewer), 25 Jun 2011, In: Biometals. 24, 6, p. 1133-1151

  Research output › peer-review

  Open Access
• 2010

  Toxicogenomic Response of Rhodospirillum rubrum S1H to the Micropollutant Triclosan

  Pycke, B., Vanermen, G., Monsieurs, P., De Wever, H., Mergeay, M., Verstraete, W., Leys, N., Mastroleo, F. (Peer reviewer), Van Houdt, R. (Peer reviewer) & Janssen, P. (Peer reviewer), 2 Apr 2010, In: Applied and Environmental Microbiology. 76, 11, p. 3503-3513

  Research output › peer-review

  Open Access
• 2009

  Experimental design and environmental parameters affect Rhodospirillum rubrum S1H response to space flight

  Mastroleo, F., Van Houdt, R., Leroy, B., Benotmane, R., Janssen, A., Mergeay, M., Vanhavere, F., Hendrickx, L., Wattiez, R., Leys, N. & Monsieurs, P. (Peer reviewer), 2 Jul 2009, In: The ISME Journal: Multidisciplinary Journal of Microbial Ecology. 3, 12, p. 1402-1419

  Research output › peer-review

  Open Access

• Molecular characterization of the life support bacterium Rhodospirillum rubrum S1H cultivated under space related environmental conditions

  Mastroleo, F. & Van Houdt, R., 23 Jan 2009, Mons, Belgium: HELHa - Haute Ecole Louvain en Hainaut. 171 p.

  Research output

  File
  879 Downloads (Pure)

• Shotgun Proteome Analysis of Rhodospirillum rubrum S1H: Integrating Data from Gel-Free and Gel-Based Peptides Fractionation Methods

  Mastroleo, F., Leroy, B., Van Houdt, R., s'Heeren, C., Mergeay, M., Hendrickx, L. & Wattiez, R., 25 Feb 2009, In: Journal of Proteome Research. 8, 5, p. 2530-2541

  Research output › peer-review

  Open Access

• The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station

  Leys, N., Baatout, S., Rosier, C., Dams, A., s'Heeren, C., Wattiez, R., Mergeay, M. & Mastroleo, F. (Peer reviewer), 2 Jul 2009, In: Antonie van Leeuwenhoek. 96, 2, p. 227-245

  Research output › peer-review

  Open Access
• 2006

  Microbial ecology of the closed artificial ecosystem MELiSSA (Micro-Ecological Life Support System Alternative)

  Hendrickx, L., De Wever, H., Hermans, V., Mastroleo, F., Morin, N., Wilmotte, A., Janssen, P. & Mergeay, M., Jan 2006, In: Research in Microbiology. 157, p. 77-86

  Research output › peer-review

  Open Access