TY - JOUR
T1 - A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil
AU - Leal, A.S.
AU - Menezes, M.A.B.C.
AU - Rodrigues, R.R.
AU - Andonie, O.
AU - Vermaercke, Peter
AU - Sneyers, Liesel
N1 - Score = 10
PY - 2008/3/7
Y1 - 2008/3/7
N2 - In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.
AB - In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.
KW - Neutron activation analysis
KW - Generic medicines
KW - Manipulated medicines
UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/ezp_90177
UR - http://knowledgecentre.sckcen.be/so2/bibref/5059
U2 - 10.1016/j.apradiso.2008.03.004
DO - 10.1016/j.apradiso.2008.03.004
M3 - Article
SN - 0969-8043
VL - 66
SP - 1307
EP - 1312
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
IS - 10
ER -