A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil

A.S. Leal, M.A.B.C. Menezes, R.R. Rodrigues, O. Andonie, Peter Vermaercke, Liesel Sneyers

    Research outputpeer-review


    In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.
    Original languageEnglish
    Pages (from-to)1307-1312
    JournalApplied Radiation and Isotopes
    Issue number10
    StatePublished - 7 Mar 2008

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