Abstract
Spaceflight and prolonged exposure to microgravity and radiation significantly impact human cardiovascular physiology, both in the short and long term. Astronauts experience physiological adaptations, including orthostatic intolerance (OI), bone loss, muscle atrophy, and cardiovascular deconditioning, with OI affecting approximately 80% of astronauts postmission. The International Space Station (ISS) serves as a vital platform for studying these effects, though space analogs on Earth are also utilized to mitigate experimental constraints. This chapter reviews key cardiovascular adaptations due to spaceflight, including changes in blood volume, stroke volume, and blood pressure, as well as accelerated cardiovascular aging caused by microgravity and radiation.
Original language | English |
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Title of host publication | Precision Medicine for Long and Safe Permanence of Humans in Space |
Publisher | Elsevier GmbH |
Pages | 507-520 |
Number of pages | 14 |
ISBN (Electronic) | 9780443222597 |
ISBN (Print) | 9780443222603 |
DOIs | |
State | Published - 1 Jan 2024 |
ASJC Scopus subject areas
- General Medicine