@article{dc1a4771e79a4082b3ce3742bdbdcdd1,
title = "Cellular dosimetry of [177Lu]Lu-DOTA-[Tyr3]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity",
abstract = "Survival and linear-quadratic model fitting parameters implemented in treatment planning for targeted radionuclide therapy depend on accurate cellular dosimetry. Therefore, we have built a refined cellular dosimetry model for [177Lu]Lu-DOTA-[Tyr3]octreotate (177Lu-DOTATATE) in vitro experiments, accounting for specific cell morphologies and sub-cellular radioactivity distributions.",
keywords = "Cellular dosimetry, [177Lu]Lu-DOTA-[Tyr3]octreotate, Polygonal mesh, S values, in vitro cytotoxicity correlation",
author = "Giulia Tamborino and {De Saint-Hubert}, Marijke and Lara Struelens and Seoane, {Dayana C.} and Ruigrok, {Eline A.M.} and An Aerts and {van Cappellen}, {Wiggert A.} and {de Jong}, Marion and Konijnenberg, {Mark W.} and Julie Nonnekens",
note = "Score=10",
year = "2020",
month = feb,
day = "10",
doi = "10.1186/s40658-020-0276-5",
language = "English",
volume = "7",
pages = "1--19",
journal = "EJNMMI Physics",
issn = "2197-7364",
publisher = "BMC (Part of Springer Nature)",
number = "8",
}