CERN-MEDICIS: A unique facility for the production of nonconventional radionuclides for the medical research

Charlotte Duchemin, João Pedro Fernandes Pinto Ramos, Thierry Stora, A. Aubert, Ermano Barbero, Vincent Barozier, Ana-Paula Bernardes, Philippe Bertreix, D. Burnel, Richard Catherall, M. Cirilli, Thomas Elias Cocolios, J. Compte, Bernard Crepieux, Matthieu Deschamps, Kristof Dockx, Alexandre Dorsival, Valentin N. Fedosseev, P. Fernier, Roberto Formento-CavaierSimone Gilardoni, Jean-Louis Grenard, Ferid Haddad, Heinke Reinhard, Moazam Khan, Ulli Koester, Laura Lambert, Giordano Lili, Lunghi Giacomo, Bruce A Marsh, Palenzuela Martinez, Fabio Pozzi, Julien Riegert, Sebastian Rothe, Francesco Riccardi, Nicolas Riggaz, Simon Stegemann, Zenip Talip, Julien Thiboud, Nicholas P. van der Meulen, Joachim Vollaire, Nhat-Tan Vuong

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    Abstract

    CERN-MEDICIS (MEDical Isotopes Collected from ISolde) is a facility at CERN (Switzerland) dedicated to the production of non-conventional radionuclides for research and development in imaging, diagnostics and radiation therapy done at partner institutes. It exploits, in a controlled radiation area suited for the handling of unsealed radioactive sources, a target irradiation station positioned between the High Resolution Separator (HRS) ISOLDE target station and its beam dump, a target remote handling system and a dedicated isotope separator beam line. It irradiates targets with the 1.4 GeV Proton Synchroton Booster (PSB), and also receives activated target materials from external institutes, notably during CERN’s Long Shut-Downs. The irradiated target is heated to high temperatures (up to 2300°C) to allow for the release of the isotopes of interest out of the target which are subsequently ionized. The ions are accelerated and the beam is steered through an offline mass separator. The radionuclide batches are, this way, extracted through mass separation and implanted into a thin metallic collection foil up to an energy of 60 keV. After collection, the isotope source is prepared to be dispatched to biomedical research centers. Since its commissioning in December 2017, the CERN-MEDICIS facility has provided non-conventional medical radionuclides such as Tb-149, Tb-152, Tb-155, Tm-165, Er-169 and Yb-175 with high specific activity, some for the first time, to research institutes and hospitals, being part of the MEDICIS collaboration, for R&D in imaging or treatment.
    Original languageEnglish
    Title of host publicationMC8: Applications ofAccelerators, Technology Transfer, Industrial Relations and Outreach
    Subtitle of host publicationTHVIR13
    PublisherJACoW Publishing
    ChapterU01 Medical Applications
    Pages75-79
    Number of pages5
    ISBN (Print)9783954502134
    StatePublished - 10 Oct 2020
    Event2020 - IPAC: 11th international particle Accelerator conference - Parc des Expositions, Caen
    Duration: 10 May 202015 May 2020
    http://www.ipac20.org

    Conference

    Conference2020 - IPAC
    Country/TerritoryFrance
    CityCaen
    Period2020-05-102020-05-15
    Internet address

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