Comparative chemical protection to the intestinal and hematopoietic systems of whole-body X-irradiated mice

Jean Maisin, D.G. Doherty

    Research outputpeer-review


    Chemical protection by AETy MEA, D-2-ABT, APMT, serotonin. and a combination of AET and serotonin of the alimentary tracts of mice against 900, 1500, 2000, and 2500 r, and the hematopoietic system after 1500 r has been studied. AET and MEA offered the best intestinal protection, AET being superior to MEA at all dose levels,. Doubling the optimal intraperitoneal dose of AET and MEA by oral administration failed to increase the degree of intestinal protection. Combined treatment with AET and serotonin, whiIe providing better protection to the bone marrow than either alone, did not increase Intestinal protection beyond
    that of AET alone.
    Original languageEnglish
    PublisherSCK CEN
    Number of pages12
    StatePublished - Nov 1963

    Publication series

    NameSCK CEN Reports
    PublisherSCK CEN

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