Convergence and divergence between the transcriptional responses to Zika virus infection and prenatal irradiation

    Research outputpeer-review

    Abstract

    In a recent paper in Cell Death and Disease, Di Cunto and co-workers found that infection of human neural progenitors (hNPCs) with Zika virus (ZIKV) induced transcriptional responses that were partly comparable to three different genetic mutations (CitK− /−, Magoh+/ −, and conditional Elp3−/− mice), which result in microcephaly in mice. The highest overlap between these different conditions was found in the activation of P53 target genes.
    Original languageEnglish
    Article numberE2672
    Pages (from-to)1-3
    Number of pages3
    JournalCell Death and Disease
    Volume8
    DOIs
    StatePublished - 16 Mar 2017

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