Etude morphologique et cytochimique des cytolysomes de la crypte duodénale de souris irradieé par rayons x

A large number of cytolysomes is prominent in the stem cells of the epithelium of the duodenal crypt of mice, few hours after a whole body irradiation, the development of these organites was followed. It seems that smooth endoplasmic reticulum and golgi vesicles take a part in the formation of the triple-layered membrane enclosing this structure. The localization of acid phosphatase was demonstrated. An increased reaction was found in the golgi zone and in numerous small vesicles soon after irradiation. Lead salt deposits are prominent in cytolysomes, first confined to the enclosed granules and, at a later stage, entirely dispersed. The morphological aspect and relationship between lysosomes and cytolysomes and also the transformation of the latter into residual bodies are discussed.