Abstract
Inherited anophthalmia was observed in the progeny of a female rat irradiated with 50 R of X-irradiation at 17 days of age. Observations on the inheritance of the condition indicated that this anophthalmia can be considered as the result of polygenic factors with incomplete penetrance. In the F2 generation 1 male was found with an unilateral anophthalmia and 1 female with a bilateral anophthalmia. R strain rats were used, as established by Muhlbock from a Wistar stock in 1947. The incidence of animals with unilateral or bilateral anophthalmia increases with the inbreeding but, even after 20 generations, some animals can have one normal eye.
| Original language | English |
|---|---|
| Pages (from-to) | 255-257 |
| Number of pages | 3 |
| Journal | Experimental Animals |
| Volume | 26 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1977 |
ASJC Scopus subject areas
- Animal Science and Zoology
- General Biochemistry,Genetics and Molecular Biology
- General Veterinary