Hypervascularization of the cerebral cortex in lead-induced encephalopathy

H. Reyners; E. Gianfelici de Reyners; J. R. Maisin

doi:10.1007/BF01937410

Hypervascularization of the cerebral cortex in lead-induced encephalopathy

H. Reyners, E. Gianfelici de Reyners, J. R. Maisin

Research output › peer-review

Abstract

Pregnant rats were fed a diet containing 1.8% lead acetate for 8 days before delivery until the young were 3 month old. The density of the cerebral cortex capillaries of the infant rats and their convolution rate were studied morphometrically and noted to increase significantly according to the duration of lead treatment, as demonstrated by two-way analysis of variance. On the other hand, the thickness of the cortex reduced progressively. The increase of both capillary density and convolution rate is supposed to be related with this involution of cortex. This provides a quantitative insight of the previously described 'capillary activation' phenomenon, caused by lead encephalopathy and reveals it as a significant sequel of saturnine action.

Original language	English
Pages (from-to)	1416-1419
Number of pages	4
Journal	Experientia
Volume	32
Issue number	11
DOIs	https://doi.org/10.1007/BF01937410
State	Published - Nov 1976

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology

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10.1007/BF01937410

Cite this

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title = "Hypervascularization of the cerebral cortex in lead-induced encephalopathy",

abstract = "Pregnant rats were fed a diet containing 1.8% lead acetate for 8 days before delivery until the young were 3 month old. The density of the cerebral cortex capillaries of the infant rats and their convolution rate were studied morphometrically and noted to increase significantly according to the duration of lead treatment, as demonstrated by two-way analysis of variance. On the other hand, the thickness of the cortex reduced progressively. The increase of both capillary density and convolution rate is supposed to be related with this involution of cortex. This provides a quantitative insight of the previously described 'capillary activation' phenomenon, caused by lead encephalopathy and reveals it as a significant sequel of saturnine action.",

author = "H. Reyners and {Gianfelici de Reyners}, E. and Maisin, {J. R.}",

year = "1976",

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AU - Gianfelici de Reyners, E.

AU - Maisin, J. R.

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N2 - Pregnant rats were fed a diet containing 1.8% lead acetate for 8 days before delivery until the young were 3 month old. The density of the cerebral cortex capillaries of the infant rats and their convolution rate were studied morphometrically and noted to increase significantly according to the duration of lead treatment, as demonstrated by two-way analysis of variance. On the other hand, the thickness of the cortex reduced progressively. The increase of both capillary density and convolution rate is supposed to be related with this involution of cortex. This provides a quantitative insight of the previously described 'capillary activation' phenomenon, caused by lead encephalopathy and reveals it as a significant sequel of saturnine action.

AB - Pregnant rats were fed a diet containing 1.8% lead acetate for 8 days before delivery until the young were 3 month old. The density of the cerebral cortex capillaries of the infant rats and their convolution rate were studied morphometrically and noted to increase significantly according to the duration of lead treatment, as demonstrated by two-way analysis of variance. On the other hand, the thickness of the cortex reduced progressively. The increase of both capillary density and convolution rate is supposed to be related with this involution of cortex. This provides a quantitative insight of the previously described 'capillary activation' phenomenon, caused by lead encephalopathy and reveals it as a significant sequel of saturnine action.

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