Influence of radioprotectors on the regeneration of the mucosa of the small intestine of mice exposed to a low dose of x-irradiation

J. R. Maisin; M. Lambiet-Collier

doi:10.1080/09553007214550061

Influence of radioprotectors on the regeneration of the mucosa of the small intestine of mice exposed to a low dose of x-irradiation

J. R. Maisin, M. Lambiet-Collier

Research output › peer-review

Abstract

The response of the stem cells of the duodenal mucosa in mice protected with AET or with a mixture of radioprotectors and exposed to 225 R of x-rays was studied. Under these conditions the protective action observed in the stem cells of the duodenum is partially masked by the biochemical shock that follows the administration of these chemicals. For the four end-points studied, a protective effect was observed only for the number of nuclei per crypt and the number of pycnotic and karyorrhectic nuclei.

Original language	English
Pages (from-to)	57-63
Number of pages	7
Journal	International Journal of Radiation Biology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1080/09553007214550061
State	Published - 1972

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

Access to Document

10.1080/09553007214550061

Cite this

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title = "Influence of radioprotectors on the regeneration of the mucosa of the small intestine of mice exposed to a low dose of x-irradiation",

abstract = "The response of the stem cells of the duodenal mucosa in mice protected with AET or with a mixture of radioprotectors and exposed to 225 R of x-rays was studied. Under these conditions the protective action observed in the stem cells of the duodenum is partially masked by the biochemical shock that follows the administration of these chemicals. For the four end-points studied, a protective effect was observed only for the number of nuclei per crypt and the number of pycnotic and karyorrhectic nuclei.",

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AB - The response of the stem cells of the duodenal mucosa in mice protected with AET or with a mixture of radioprotectors and exposed to 225 R of x-rays was studied. Under these conditions the protective action observed in the stem cells of the duodenum is partially masked by the biochemical shock that follows the administration of these chemicals. For the four end-points studied, a protective effect was observed only for the number of nuclei per crypt and the number of pycnotic and karyorrhectic nuclei.

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