Purpose: RENEB, ‘Realising the European Network of Biodosimetry and Physical Retrospective
Dosimetry,’ is a network for research and emergency response mutual assistance in biodosimetry within
the EU. Within this extremely active network, a number of new dosimetry methods have recently been
proposed or developed. There is a requirement to test and/or validate these candidate techniques and
inter-comparison exercises are a well-established method for such validation.
Materials and methods: The authors present details of inter-comparisons of four such new methods:
dicentric chromosome analysis including telomere and centromere staining; the gene expression assay
carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiationinduced
thermoluminescent signals in glass screens taken from mobile phones.
Results: In general the results show good agreement between the laboratories and methods within the
expected levels of uncertainty, and thus demonstrate that there is a lot of potential for each of the candidate
Conclusions: Further work is required before the new methods can be included within the suite of reliable
dosimetry methods for use by RENEB partners and others in routine and emergency response