Intercomparison and performance assessment of radionuclide calibrators used in nuclear medicine departments in Serbia

Milos Zivanovic; Ivana S. Vukanac; Jelena Samac; Marija Jeremic; Drina Jankovic; Aleksandar Kandić; Clarita Saldarriaga Vargas; Lara Struelens; Olivera F. Ciraj-Bjelac

doi:10.1016/j.apradiso.2021.110013

Intercomparison and performance assessment of radionuclide calibrators used in nuclear medicine departments in Serbia

Milos Zivanovic, Ivana S. Vukanac, Jelena Samac, Marija Jeremic, Drina Jankovic, Aleksandar Kandić, Clarita Saldarriaga Vargas, Lara Struelens, Olivera F. Ciraj-Bjelac

Research output › peer-review

Abstract

The purpose of this work is to assess accuracy and compare the performance of radionuclide calibrators (RNCs) used in nuclear medicine departments in Serbia. Testing of the RNCs included verification of measurement accuracy, as well as analysis of routinely used quality control protocols, by using the certified radioactivity standards (57Co, 137Cs). RNCs performances were assessed with 99mTc through comparison of reference value for radionuclide activity and RNC measurements. Results of the intercomparison revealed that RNCs, 15 in total, are accurate within 10% in vial geometry and within 15% in syringe geometry. Most of them showed similar performance. The results revealed that container geometry is an important influencing parameter in the accuracy of activity measurement. Obtained results indicate a need for regular calibration and implementation of Quality Control program in order to achieve and maintain the accuracy of activity measurements in nuclear medicine.

Original language	English
Article number	110013
Pages (from-to)	1-7
Number of pages	7
Journal	Applied Radiation and Isotopes
Volume	179
DOIs	https://doi.org/10.1016/j.apradiso.2021.110013
State	Published - 29 Oct 2021

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Zivanovic, M., Vukanac, I. S., Samac, J., Jeremic, M., Jankovic, D., Kandić, A., Saldarriaga Vargas, C., Struelens, L., & Ciraj-Bjelac, O. F. (2021). Intercomparison and performance assessment of radionuclide calibrators used in nuclear medicine departments in Serbia. Applied Radiation and Isotopes, 179, 1-7. Article 110013. https://doi.org/10.1016/j.apradiso.2021.110013

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abstract = "The purpose of this work is to assess accuracy and compare the performance of radionuclide calibrators (RNCs) used in nuclear medicine departments in Serbia. Testing of the RNCs included verification of measurement accuracy, as well as analysis of routinely used quality control protocols, by using the certified radioactivity standards (57Co, 137Cs). RNCs performances were assessed with 99mTc through comparison of reference value for radionuclide activity and RNC measurements. Results of the intercomparison revealed that RNCs, 15 in total, are accurate within 10% in vial geometry and within 15% in syringe geometry. Most of them showed similar performance. The results revealed that container geometry is an important influencing parameter in the accuracy of activity measurement. Obtained results indicate a need for regular calibration and implementation of Quality Control program in order to achieve and maintain the accuracy of activity measurements in nuclear medicine.",

keywords = "Radionuclide calibrators, Intercomparison study, Performance testing, Accuracy, Stability, Precision, Linearity",

author = "Milos Zivanovic and Vukanac, {Ivana S.} and Jelena Samac and Marija Jeremic and Drina Jankovic and Aleksandar Kandi{\'c} and {Saldarriaga Vargas}, Clarita and Lara Struelens and Ciraj-Bjelac, {Olivera F.}",

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AU - Zivanovic, Milos

AU - Vukanac, Ivana S.

AU - Samac, Jelena

AU - Jeremic, Marija

AU - Jankovic, Drina

AU - Kandić, Aleksandar

AU - Saldarriaga Vargas, Clarita

AU - Struelens, Lara

AU - Ciraj-Bjelac, Olivera F.

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AB - The purpose of this work is to assess accuracy and compare the performance of radionuclide calibrators (RNCs) used in nuclear medicine departments in Serbia. Testing of the RNCs included verification of measurement accuracy, as well as analysis of routinely used quality control protocols, by using the certified radioactivity standards (57Co, 137Cs). RNCs performances were assessed with 99mTc through comparison of reference value for radionuclide activity and RNC measurements. Results of the intercomparison revealed that RNCs, 15 in total, are accurate within 10% in vial geometry and within 15% in syringe geometry. Most of them showed similar performance. The results revealed that container geometry is an important influencing parameter in the accuracy of activity measurement. Obtained results indicate a need for regular calibration and implementation of Quality Control program in order to achieve and maintain the accuracy of activity measurements in nuclear medicine.

KW - Radionuclide calibrators

KW - Intercomparison study

KW - Performance testing

KW - Accuracy

KW - Stability

KW - Precision

KW - Linearity

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