The energy response of gafchromic films and different kinds of thermoluminescence (TL) dosimeters were studied. Detectors were exposed to various beam qualities. After laboratory studies, detectors were used in hospitals to determine maximum skin dose (MSD) during clinical interventional radiology (IR) procedures. It was observed that the calibration process of Gafchromic films could introduce significant uncertainties in MSD measurement mainly due to energy and non-linear dose response. TL detectors were able to measure dose with lower uncertainty. However, the use of TL detectors is more time-consuming and the location of the MSD on the patient can be missed. Measurements performed with TL foils lead to good agreement in “high” dose range (several hundreds of mGy). TL foils could represent the most adapted tool for the assessment of fluoroscopy-induced skin doses. However, since they are not commercially available nowadays their application in clinical practice is limited.