Localisation intracellulaire, dans le foie de rat, d'un facteur inhibiteur de la synthèse de l'acide désoxyribonucléique in vitro

R. Goutier; I. Bologna

Localisation intracellulaire, dans le foie de rat, d'un facteur inhibiteur de la synthèse de l'acide désoxyribonucléique in vitro

R. Goutier, I. Bologna

Research output › peer-review

Abstract

We measured the in vitro synthesis of DNA in the presence of aqueous extracts of
regeneratirig rat livers. Suuspensions of microsomes from normal liver powerfully
inhibit this incorporation. The observed inhibition is not due to a hydrolysis of primer DNA by alkaline DNAase (EC 3.1.4.5) nor to a dephosphorylation of the precursors by phosphatases.
Microsomes prepared from regeneratmg livers have a smaller inhibitory power
than that of normal liver microsomes.

Original language	English
Publisher	SCK CEN
Number of pages	11
State	Published - Nov 1962
Externally published	Yes

Publication series

Name	SCK CEN Reports
Publisher	SCK CEN
No.	BLG-206

Cite this

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title = "Localisation intracellulaire, dans le foie de rat, d'un facteur inhibiteur de la synth{\`e}se de l'acide d{\'e}soxyribonucl{\'e}ique in vitro",

abstract = "We measured the in vitro synthesis of DNA in the presence of aqueous extracts ofregeneratirig rat livers. Suuspensions of microsomes from normal liver powerfullyinhibit this incorporation. The observed inhibition is not due to a hydrolysis of primer DNA by alkaline DNAase (EC 3.1.4.5) nor to a dephosphorylation of the precursors by phosphatases.Microsomes prepared from regeneratmg livers have a smaller inhibitory powerthan that of normal liver microsomes.",

author = "R. Goutier and I. Bologna",

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N2 - We measured the in vitro synthesis of DNA in the presence of aqueous extracts ofregeneratirig rat livers. Suuspensions of microsomes from normal liver powerfullyinhibit this incorporation. The observed inhibition is not due to a hydrolysis of primer DNA by alkaline DNAase (EC 3.1.4.5) nor to a dephosphorylation of the precursors by phosphatases.Microsomes prepared from regeneratmg livers have a smaller inhibitory powerthan that of normal liver microsomes.

AB - We measured the in vitro synthesis of DNA in the presence of aqueous extracts ofregeneratirig rat livers. Suuspensions of microsomes from normal liver powerfullyinhibit this incorporation. The observed inhibition is not due to a hydrolysis of primer DNA by alkaline DNAase (EC 3.1.4.5) nor to a dephosphorylation of the precursors by phosphatases.Microsomes prepared from regeneratmg livers have a smaller inhibitory powerthan that of normal liver microsomes.

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