Localisation intracellulaire, dans le foie de rat, d'un facteur inhibiteur de la synthèse de l'acide désoxyribonucléique in vitro

R. Goutier, I. Bologna

Research outputpeer-review


We measured the in vitro synthesis of DNA in the presence of aqueous extracts of
regeneratirig rat livers. Suuspensions of microsomes from normal liver powerfully
inhibit this incorporation. The observed inhibition is not due to a hydrolysis of primer DNA by alkaline DNAase (EC nor to a dephosphorylation of the precursors by phosphatases.
Microsomes prepared from regeneratmg livers have a smaller inhibitory power
than that of normal liver microsomes.
Original languageEnglish
PublisherSCK CEN
Number of pages11
StatePublished - Nov 1962
Externally publishedYes

Publication series

NameSCK CEN Reports
PublisherSCK CEN

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