Metabolism of deoxycytidine in isolated perfused organs

G. B. Gerber; B. Zicha; J. Deroo; J. P. de Cock; E. Geyer

doi:10.1007/BF01190619

Metabolism of deoxycytidine in isolated perfused organs

G. B. Gerber, B. Zicha, J. Deroo, J. P. de Cock, E. Geyer

Research output › peer-review

Abstract

The metabolism of deoxycytidine-U-¹⁴C was studied in isolated perfused normal and regenerating rat liver, in perfused rat intestine and in isolated perfused mouse liver. A technique to perfuse mouse liver is described. Catabolism of dCyd is very slow in organs of the rat whereas it is rapid in those of the mouse. Nevertheless, incorporation into liver DNA does not differ markedly between the species. The quantitative aspects of dCyd metabolism in the isolated organs are discussed.

Original language	English
Pages (from-to)	333-341
Number of pages	9
Journal	Biophysik
Volume	8
Issue number	4
DOIs	https://doi.org/10.1007/BF01190619
State	Published - Dec 1972

ASJC Scopus subject areas

Radiation
Biophysics
Environmental Chemistry
Radiology Nuclear Medicine and imaging
Environmental Science (miscellaneous)
General Environmental Science
Agricultural and Biological Sciences (miscellaneous)
Physics and Astronomy (miscellaneous)

Access to Document

10.1007/BF01190619

Cite this

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title = "Metabolism of deoxycytidine in isolated perfused organs",

abstract = "The metabolism of deoxycytidine-U-14C was studied in isolated perfused normal and regenerating rat liver, in perfused rat intestine and in isolated perfused mouse liver. A technique to perfuse mouse liver is described. Catabolism of dCyd is very slow in organs of the rat whereas it is rapid in those of the mouse. Nevertheless, incorporation into liver DNA does not differ markedly between the species. The quantitative aspects of dCyd metabolism in the isolated organs are discussed.",

author = "Gerber, {G. B.} and B. Zicha and J. Deroo and {de Cock}, {J. P.} and E. Geyer",

year = "1972",

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AU - Zicha, B.

AU - Deroo, J.

AU - de Cock, J. P.

AU - Geyer, E.

PY - 1972/12

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