Microdosimetric simulations of carbon ions using the monte carlo code fluka

Therapeutic carbon ion beams produce a complex and variable radiation field that changes along the penetration depth due to the high density of energy loss along the particle track together with the secondary particles produced by nuclear fragmentation reactions. An accurate physical characterisation of such complex mixed-radiation fields can be performed by measuring microdosimetric spectra with mini tissue-equivalent proportional counters (mini-TEPCs), which are one of the most accurate devices used in experimental microdosimetry. Numerical calculations with Monte Carlo codes such as FLUKA can be used to supplement experimental microdosimetric measurements performed with TEPCs, but the nuclear cross sections and fragmentation models need to be benchmarked with experimental data for different energies and scenarios. The aim of this work is to compare experimental carbon microdosimetric data measured with the mini TEPC with calculated microdosimetry spectra obtained with FLUKA for 12C ions of 189.5 MeV/u in the Bragg peak region