Microdosimetry with a sealed mini-TEPC and a silicon telescope at a clinical proton SOBP of CATANA

Anna Bianchi, Anna Selva, Paolo Colautti, Davide Bortot, Davide Mazzucconi, Andrea Pola, Stefano Agosteo, Giada Petringa, G. A. Pablo Cirrone, Brigitte Reniers, Alessio Parisi, Lara Struelens, Filip Vanhavere, Valeria Conte

Research outputpeer-review


A sealed miniaturized Tissue Equivalent Proportional Counter (mini-TEPC) able to work in gas-steady modality was developed at the Legnaro National Laboratories of the Italian National Institute of Nuclear Physics (LNL – INFN, Legnaro, Italy). The aim of the present work is to compare the response of this mini-TEPC with that of a silicon microdosimeter based on a monolithic telescope. Pairwise measurements were performed at the 62 MeV proton clinical Spread Out Bragg Peak (SOBP) of CATANA at the Southern National Laboratories of INFN (LNS – INFN, Catania, Italy). The dose mean lineal energy values were derived from the spectra measured with the two detectors and compared with the total dose averaged LET calculated by means of Geant4 Monte Carlo simulations. Finally, the possibility to apply the Microdosimetric Kinetic Model (MKM) to reproduce RBE variations with depth along the Spread Out Bragg Peak was investigated.
Original languageEnglish
Article number108730
JournalRadiation Physics and Chemistry
StatePublished - 1 Feb 2020

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