TY - JOUR
T1 - Molecular Mechanisms Underlying Bacterial Uranium Resistance
AU - Rogiers, Tom
AU - Van Houdt, Rob
AU - Williamson, Adam
AU - Leys, Natalie
AU - Boon, Nico
AU - Mijnendonckx, Kristel
N1 - Score=10
PY - 2022/3/10
Y1 - 2022/3/10
N2 - Environmental uranium pollution due to industries producing naturally occurring radioactive material or nuclear accidents and releases is a global concern. Uranium is hazardous for ecosystems as well as for humans when accumulated through the food chain, through contaminated groundwater and potable water sources, or through inhalation. In particular, uranium pollution pressures microbial communities, which are essential for healthy ecosystems. In turn, microorganisms can influence the mobility and toxicity of uranium through processes like biosorption, bioreduction, biomineralization, and bioaccumulation. These processes were characterized by studying the interaction of different bacteria with uranium. However, most studies unraveling the underlying molecular mechanisms originate from the last decade. Molecular mechanisms help to understand how bacteria interact with radionuclides in the environment. Furthermore, knowledge on these underlying mechanisms could be exploited to improve bioremediation technologies. Here, we review the current knowledge on bacterial uranium resistance and how this could be used for bioremediation applications.
AB - Environmental uranium pollution due to industries producing naturally occurring radioactive material or nuclear accidents and releases is a global concern. Uranium is hazardous for ecosystems as well as for humans when accumulated through the food chain, through contaminated groundwater and potable water sources, or through inhalation. In particular, uranium pollution pressures microbial communities, which are essential for healthy ecosystems. In turn, microorganisms can influence the mobility and toxicity of uranium through processes like biosorption, bioreduction, biomineralization, and bioaccumulation. These processes were characterized by studying the interaction of different bacteria with uranium. However, most studies unraveling the underlying molecular mechanisms originate from the last decade. Molecular mechanisms help to understand how bacteria interact with radionuclides in the environment. Furthermore, knowledge on these underlying mechanisms could be exploited to improve bioremediation technologies. Here, we review the current knowledge on bacterial uranium resistance and how this could be used for bioremediation applications.
KW - Reduction
KW - Phosphatases
KW - Efflux systems
KW - Regulation
KW - Bioremediation
UR - https://ecm.sckcen.be/OTCS/llisapi.dll/open/48596805
U2 - 10.3389/fmicb.2022.822197
DO - 10.3389/fmicb.2022.822197
M3 - Article
SN - 1664-302X
VL - 13
SP - 1
EP - 19
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
M1 - 822197
ER -