Mutagenicity tests with griseofulvin

A. Léonard; F. Poncelet; G. Grutman; E. Carbonelle; L. Fabry

doi:10.1016/0165-1218(79)90154-X

Mutagenicity tests with griseofulvin

A. Léonard, F. Poncelet, G. Grutman, E. Carbonelle, L. Fabry

Research output › peer-review

Abstract

Griseofulvin was studied for its ability to induce structural chromosomal aberrations in germ and somatic cells of the male mouse. It was also tested for its capacity to produce his⁺ revertants in Salmonella typhimurium. All tests yielded negative results, whereas highly significant effects were recorded in control assays with thio-TEPA.

Original language	English
Pages (from-to)	225-234
Number of pages	10
Journal	Mutation Research/Genetic Toxicology
Volume	68
Issue number	3
DOIs	https://doi.org/10.1016/0165-1218(79)90154-X
State	Published - Nov 1979

ASJC Scopus subject areas

Toxicology
Genetics

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10.1016/0165-1218(79)90154-X

Cite this

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title = "Mutagenicity tests with griseofulvin",

abstract = "Griseofulvin was studied for its ability to induce structural chromosomal aberrations in germ and somatic cells of the male mouse. It was also tested for its capacity to produce his+ revertants in Salmonella typhimurium. All tests yielded negative results, whereas highly significant effects were recorded in control assays with thio-TEPA.",

author = "A. L{\'e}onard and F. Poncelet and G. Grutman and E. Carbonelle and L. Fabry",

year = "1979",

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doi = "10.1016/0165-1218(79)90154-X",

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pages = "225--234",

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T1 - Mutagenicity tests with griseofulvin

AU - Léonard, A.

AU - Poncelet, F.

AU - Grutman, G.

AU - Carbonelle, E.

AU - Fabry, L.

PY - 1979/11

Y1 - 1979/11

N2 - Griseofulvin was studied for its ability to induce structural chromosomal aberrations in germ and somatic cells of the male mouse. It was also tested for its capacity to produce his+ revertants in Salmonella typhimurium. All tests yielded negative results, whereas highly significant effects were recorded in control assays with thio-TEPA.

AB - Griseofulvin was studied for its ability to induce structural chromosomal aberrations in germ and somatic cells of the male mouse. It was also tested for its capacity to produce his+ revertants in Salmonella typhimurium. All tests yielded negative results, whereas highly significant effects were recorded in control assays with thio-TEPA.

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U2 - 10.1016/0165-1218(79)90154-X

DO - 10.1016/0165-1218(79)90154-X

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AN - SCOPUS:0018682563

SN - 0165-1218

VL - 68

SP - 225

EP - 234

JO - Mutation Research/Genetic Toxicology

JF - Mutation Research/Genetic Toxicology

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