Online 2D dose verification required in UHDR-FLASH preclinical research: challenges and possibilities

Verdi Vanreusel; Stephen Brown; Shujat Ali; Dirk Verellen; Luana de Freitas Nascimento

Online 2D dose verification required in UHDR-FLASH preclinical research: challenges and possibilities

Verdi Vanreusel
, Stephen Brown
, Shujat Ali
, Dirk Verellen
, Luana de Freitas Nascimento

Radiation Protection

Research output › peer-review

Abstract

The increasing interest in FLASH-RT has lead to both the development of new, and the conversion of existing linear accelerators to enable ultra-high dose rate (UHDR) irradiations for preclinical research. Dosimetry in this setting remains challenging with several crucial aspects missing. This work shows the challenges and need for real-time 2D UHDR dosimetry, and presents a solution in the context of preclinical irradiations in a non-homogeneous electron beam.

Original language	English
Pages (from-to)	S2590-S2592
Number of pages	3
Journal	Radiotherapy & Oncology
Volume	206
State	Published - May 2025
Event	2025 - ESTRO - Vienna Duration: 2 May 2025 → 6 May 2025

Access to Document

https://www.thegreenjournal.com/article/S0167-8140(25)00745-5/fulltextLicense: Unspecified

Cite this

@article{899bc4d66061444085f09c4171193363,

title = "Online 2D dose verification required in UHDR-FLASH preclinical research: challenges and possibilities",

abstract = "The increasing interest in FLASH-RT has lead to both the development of new, and the conversion of existing linear accelerators to enable ultra-high dose rate (UHDR) irradiations for preclinical research. Dosimetry in this setting remains challenging with several crucial aspects missing. This work shows the challenges and need for real-time 2D UHDR dosimetry, and presents a solution in the context of preclinical irradiations in a non-homogeneous electron beam.",

keywords = "2D real-time dosimetry, UHDR-FLASH dosimetry",

author = "Verdi Vanreusel and Stephen Brown and Shujat Ali and Dirk Verellen and \{de Freitas Nascimento\}, Luana",

note = "Score=3; 2025 - ESTRO ; Conference date: 02-05-2025 Through 06-05-2025",

year = "2025",

month = may,

language = "English",

volume = "206",

pages = "S2590--S2592",

journal = "Radiotherapy \& Oncology",

publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - Online 2D dose verification required in UHDR-FLASH preclinical research: challenges and possibilities

AU - Vanreusel, Verdi

AU - Brown, Stephen

AU - Ali, Shujat

AU - Verellen, Dirk

AU - de Freitas Nascimento, Luana

N1 - Score=3

PY - 2025/5

Y1 - 2025/5

N2 - The increasing interest in FLASH-RT has lead to both the development of new, and the conversion of existing linear accelerators to enable ultra-high dose rate (UHDR) irradiations for preclinical research. Dosimetry in this setting remains challenging with several crucial aspects missing. This work shows the challenges and need for real-time 2D UHDR dosimetry, and presents a solution in the context of preclinical irradiations in a non-homogeneous electron beam.

AB - The increasing interest in FLASH-RT has lead to both the development of new, and the conversion of existing linear accelerators to enable ultra-high dose rate (UHDR) irradiations for preclinical research. Dosimetry in this setting remains challenging with several crucial aspects missing. This work shows the challenges and need for real-time 2D UHDR dosimetry, and presents a solution in the context of preclinical irradiations in a non-homogeneous electron beam.

KW - 2D real-time dosimetry

KW - UHDR-FLASH dosimetry

M3 - Meeting abstract

VL - 206

SP - S2590-S2592

JO - Radiotherapy & Oncology

JF - Radiotherapy & Oncology

T2 - 2025 - ESTRO

Y2 - 2 May 2025 through 6 May 2025

ER -