Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy

Simon Stegemann, Thomas Elias Cocolios, Kristof Dockx, Gregory Leinders, Lucia Popescu, João Pedro Fernandes Pinto Ramos, Marc Verwerft, Kim Rijpstra, Thierry Stora, Jef Vleugels

    Research outputpeer-review


    A novel production system based on the ISOL method is being
    developed to produce intense mass separated $^{11}$C beams for PET-aided
    hadron therapy. This work presents a systematic study on the target-ion
    source developments optimized for $^{11}$C beam production. A solid
    boron nitride target (BN) with approximately 21$\%$ open porosity was
    manufactured by spark plasma sintering to provide maximized in-target
    production yield with enhanced isotope release properties. Operational
    limitations with respect to high temperatures and oxidizing atmospheres
    were studied, revealing that the BN target can withstand temperatures up
    to 1500 $\degree$C and can be operated with a controlled O$_2$ leak,
    providing O$_2$ potentials up to $-$300 kJ/mol, measured at 1000
    Original languageEnglish
    Pages (from-to)403-407
    Number of pages5
    JournalNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
    Early online date30 May 2019
    StatePublished - 15 Jan 2020

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