TY - JOUR
T1 - Production of Sn-117m in the BR2 high-flux reactor
AU - Ponsard, Bernard
AU - Srivastava, Suresh C.
AU - Mausner, Leonard F.
AU - Knapp, Russ F.F.
AU - Garland, Marc A.
AU - Mirzadeh, Saed
N1 - Score=10
PY - 2009/7/1
Y1 - 2009/7/1
N2 - The BR2 reactor is a 100 MWth high-flux ‘materials testing reactor’, which produces a wide range of radioisotopes for various applications in nuclear medicine and industry. Tin-117m (117mSn), a promising radionuclide for therapeutic applications, and its production have been validated in the BR2 reactor. In contrast to therapeutic beta emitters, 117mSn decays via isomeric transition with the emission of monoenergetic conversion electrons which are effective for metastatic bone pain palliation and radiosynovectomy with lesser damage to the bone marrow and the healthy tissues. Furthermore, the emitted gamma photons are ideal for imaging and dosimetry.
AB - The BR2 reactor is a 100 MWth high-flux ‘materials testing reactor’, which produces a wide range of radioisotopes for various applications in nuclear medicine and industry. Tin-117m (117mSn), a promising radionuclide for therapeutic applications, and its production have been validated in the BR2 reactor. In contrast to therapeutic beta emitters, 117mSn decays via isomeric transition with the emission of monoenergetic conversion electrons which are effective for metastatic bone pain palliation and radiosynovectomy with lesser damage to the bone marrow and the healthy tissues. Furthermore, the emitted gamma photons are ideal for imaging and dosimetry.
KW - BR2 high-flux reactor
KW - Medical isotopes
KW - 117mSn
KW - Bone pain palliation
KW - Radiosynovectomy
UR - https://ecm.sckcen.be/OTCS/llisapi.dll/overview/39019097
U2 - 10.1016/j.apradiso.2009.02.023
DO - 10.1016/j.apradiso.2009.02.023
M3 - Article
SN - 0969-8043
VL - 67
SP - 1158
EP - 1161
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
IS - 7-8
ER -