Radioprotecteurs et cancers

J. R. Maisin; J. Hugon; Alain Leonard

Radioprotecteurs et cancers

J. R. Maisin, J. Hugon, Alain Leonard

Research output › peer-review

Abstract

We have shown that AET penetrates normal and cancerous tissues of mice with ease and without distinction. Even though AET afforded the same protection against radiation damage to cancer and normal tissues, it was possible, under special experimental conditions, to prolong greatly the survival of mice implanted with Landschütz ascites cells by administering AET prior to X-irradiation.
We have also found that from 10 to 30 % of the mice protected by the combined administration of AET, gluthatione and serotonin, prior to the exposure to an X-ray dose of 2000 r, were still alive after 30 days.

Original language	English
Publisher	SCK CEN
Number of pages	19
State	Published - Nov 1964

Publication series

Name	SCK CEN Reports
Publisher	SCK CEN
No.	BLG-352

Cite this

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title = "Radioprotecteurs et cancers",

abstract = "We have shown that AET penetrates normal and cancerous tissues of mice with ease and without distinction. Even though AET afforded the same protection against radiation damage to cancer and normal tissues, it was possible, under special experimental conditions, to prolong greatly the survival of mice implanted with Landsch{\"u}tz ascites cells by administering AET prior to X-irradiation.We have also found that from 10 to 30 % of the mice protected by the combined administration of AET, gluthatione and serotonin, prior to the exposure to an X-ray dose of 2000 r, were still alive after 30 days.",

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AB - We have shown that AET penetrates normal and cancerous tissues of mice with ease and without distinction. Even though AET afforded the same protection against radiation damage to cancer and normal tissues, it was possible, under special experimental conditions, to prolong greatly the survival of mice implanted with Landschütz ascites cells by administering AET prior to X-irradiation.We have also found that from 10 to 30 % of the mice protected by the combined administration of AET, gluthatione and serotonin, prior to the exposure to an X-ray dose of 2000 r, were still alive after 30 days.

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