Role of Quorum Sensing in Resistance of Serratia plymuthica against Acanthamoeba castellanii

Eva Wevers, Pieter Moons, Rob Van Houdt, Abram Aertsen, Chris W. Michiels, Max Mergeay

    Research outputpeer-review

    Abstract

    Free-living amoebae such as Acanthamoeba castellanii are ubiquitous in aquatic environments and most soil. They feed on bacteria which are ingested by phagocytosis and digested within food vacuoles. In this typical predator prey relationship bacteria are exposed to selection pressure by grazing of amoebae which caused the development of amoeba resistant bacteria. In this study the influence of the Serratia plymuthica quorum sensing system on its resistance against A. castellanii was investigated and apparently this system affects resistance. Further experiments will try to link this resistance to any of the known quorum sensing-regulated phenotypes.
    Original languageEnglish
    Title of host publicationNovel compounds and strategies to combat pathogenic microorganisms
    Place of PublicationLeuven, Belgium
    Pages132-132
    StatePublished - 24 Nov 2006
    EventRole of Quorum Sensing in Resistance of Serratia plymuthica against Acanthamoeba castellanii - Brussels
    Duration: 24 Nov 200624 Nov 2006

    Conference

    ConferenceRole of Quorum Sensing in Resistance of Serratia plymuthica against Acanthamoeba castellanii
    Country/TerritoryBelgium
    CityBrussels
    Period2006-11-242006-11-24

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