Abstract
Radiation leukemia virus (RadLV)-induced lymphomas of C57BL mice display the appearance of novel proviral sequences at common sites of their DNAs. These results are compatible with the hypothesis of viral oncogenesis by promotor insertion. Radiation-induced tumors do not acquire a detectable novel provirus, suggesting that activation of a transforming gene proceeds by a mechanism distinct from the former.
Translated title of the contribution | Common proviral integration sites in C57BL mouse lymphomas induced by RadLV and absence of novel proviral sequences in radiogenic lymphoma DNA |
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Original language | French |
Pages (from-to) | 411-419 |
Number of pages | 9 |
Journal | Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales |
Volume | 176 |
Issue number | 3 |
State | Published - 1982 |
ASJC Scopus subject areas
- General Biochemistry,Genetics and Molecular Biology