Abstract
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology.
| Original language | English |
|---|---|
| Title of host publication | Stress Challenges and Immunity in Space |
| Subtitle of host publication | From mechanisms to monitoring and preventive strategies (Springer, second edition, 2020) |
| Place of Publication | Switzerland |
| Publisher | Springer |
| Pages | 373-404 |
| Volume | 1 |
| Edition | Second edition |
| ISBN (Electronic) | 978-3-030-16996-1 |
| ISBN (Print) | 978-3-030-16995-4 |
| DOIs | |
| State | Published - 1 Jan 2020 |