Studies on detoxication by the perfused liver: I. Hippuric acid synthesis after irradiation

G. B. Gerber, J. Remy-Defraigne

Research outputpeer-review

Abstract

Synthesis of hippuric acid was determined in the isolated perfused liver of normal and x-irradiated rats with and without addition of glycine. An increase in synthesis of hippuric acid without addition of glycine was found in x-irradiated liver, indicating an expansion of the free glycine pool. On the other hand, synthesis of hippuric acid in x-irradiated liver was found to be slightly decreased when large amounts of glycine were present in the perfusate.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalInternational Journal of Radiation Biology
Volume7
Issue number1
DOIs
StatePublished - 1963
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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