@article{6b41008ab02d4a4282740c30d13e67bc,
title = "Surface proteins of radiation-induced and radiation leukemia virus-induced thymic lymphosarcomas in mice",
abstract = "Thymic lymphosarcomas (TLS) were induced in C57BL mice by X-rays or by Radiation Leukemia Virus (RadLV) and their surface glycoproteins (gps) compared after cell-surface radio-iodination and polyacrylamide gel electrophoresis (SDS-PAGE). All lymphocytic antigens tested (T200, 170 100, Thy-1) and proteins with apparent molecular weight (Mr) around 120,000 and 100,000 were present on all tumours, as well as retrovirus - encoded proteins but considerable variation in the Mr of several serologically-related proteins was observed. Therefore, the TLS in C57BL mice form a heterogeneous group, suggesting that T cells can be transformed at different stages of maturation. The possibility that transformation allows or even triggers differentiation is also entertained.",
keywords = "differentiation, glycoprotein, lectins, membrane, monoclonal antibody, radiation, retrovirus, T lymphocyte",
author = "Hooghe, \{Robert J.\} and Hoessli, \{Daniel C.\} and Michel Janowski",
year = "1983",
doi = "10.1016/0145-2126(83)90010-3",
language = "English",
volume = "7",
pages = "205--213,215--219",
journal = "Leukemia Research",
issn = "0145-2126",
publisher = "Elsevier Ltd",
number = "2",
}