Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals

Andrew Burgoyne; Maarten Ooms; Thomas Cardinaels; Dennis Elema

doi:10.1002/jlcr.3725

Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals

Andrew Burgoyne, Maarten Ooms, Thomas Cardinaels, Dennis Elema

Research output › peer-review

Abstract

161Tb has many attractive properties (half‐life of 6.9 d, β−decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies.1 161Tb can be produced via neutron irradiation of 160Gd in a nuclear reactor, such as BR2(flux of circa 1014 neutrons cm−2 s−1) at SCK•CEN. The aim of this project was to develop a fast and easy method
to purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in‐house chelator design

Original language	English
Title of host publication	Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019
Pages	S303-S303
Number of pages	1
Volume	62
DOIs	https://doi.org/10.1002/jlcr.3725
State	Published - 24 May 2019
Event	ISRS 2019 - SRS Office, Beijing Duration: 26 May 2019 → 31 May 2019 https://www.srsweb.org/isrs2019

Publication series

Name	Journal of Labelled Compounds and Radiopharmaceuticals
Publisher	Wiley - John Wiley & Sons, Ltd
ISSN (Print)	0362-4803

Conference

Conference	ISRS 2019
Country/Territory	China
City	Beijing
Period	2019-05-26 → 2019-05-31
Internet address	https://www.srsweb.org/isrs2019

Access to Document

10.1002/jlcr.3725License: Unspecified

Cite this

Burgoyne, A., Ooms, M., Cardinaels, T., & Elema, D. (2019). Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals. In Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019 (Vol. 62, pp. S303-S303). (Journal of Labelled Compounds and Radiopharmaceuticals). https://doi.org/10.1002/jlcr.3725

Burgoyne, Andrew ; Ooms, Maarten ; Cardinaels, Thomas et al. / Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160 : Poster Category: Radiochemistry ‐ Radiometals. Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019. Vol. 62 2019. pp. S303-S303 (Journal of Labelled Compounds and Radiopharmaceuticals).

@inproceedings{7f4614b224d3414fbc05a6947ff38217,

title = "Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals",

abstract = "161Tb has many attractive properties (half‐life of 6.9 d, β−decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies.1 161Tb can be produced via neutron irradiation of 160Gd in a nuclear reactor, such as BR2(flux of circa 1014 neutrons cm−2 s−1) at SCK•CEN. The aim of this project was to develop a fast and easy methodto purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in‐house chelator design",

keywords = "BR2, 161Tb",

author = "Andrew Burgoyne and Maarten Ooms and Thomas Cardinaels and Dennis Elema",

note = "Score=3; ISRS 2019 ; Conference date: 26-05-2019 Through 31-05-2019",

year = "2019",

month = may,

day = "24",

doi = "10.1002/jlcr.3725",

language = "English",

volume = "62",

series = "Journal of Labelled Compounds and Radiopharmaceuticals",

publisher = "Wiley - John Wiley & Sons, Ltd",

pages = "S303--S303",

booktitle = "Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019",

url = "https://www.srsweb.org/isrs2019",

}

Burgoyne, A, Ooms, M , Cardinaels, T & Elema, D 2019, Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals. in Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019. vol. 62, Journal of Labelled Compounds and Radiopharmaceuticals, pp. S303-S303, ISRS 2019, Beijing, China, 2019-05-26. https://doi.org/10.1002/jlcr.3725

Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals. / Burgoyne, Andrew; Ooms, Maarten ; Cardinaels, Thomas et al.
Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019. Vol. 62 2019. p. S303-S303 (Journal of Labelled Compounds and Radiopharmaceuticals).

Research output › peer-review

TY - GEN

T1 - Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160

T2 - ISRS 2019

AU - Burgoyne, Andrew

AU - Ooms, Maarten

AU - Cardinaels, Thomas

AU - Elema, Dennis

N1 - Score=3

PY - 2019/5/24

Y1 - 2019/5/24

N2 - 161Tb has many attractive properties (half‐life of 6.9 d, β−decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies.1 161Tb can be produced via neutron irradiation of 160Gd in a nuclear reactor, such as BR2(flux of circa 1014 neutrons cm−2 s−1) at SCK•CEN. The aim of this project was to develop a fast and easy methodto purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in‐house chelator design

AB - 161Tb has many attractive properties (half‐life of 6.9 d, β−decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies.1 161Tb can be produced via neutron irradiation of 160Gd in a nuclear reactor, such as BR2(flux of circa 1014 neutrons cm−2 s−1) at SCK•CEN. The aim of this project was to develop a fast and easy methodto purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in‐house chelator design

KW - BR2

KW - 161Tb

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/34446471

U2 - 10.1002/jlcr.3725

DO - 10.1002/jlcr.3725

M3 - In-proceedings paper

VL - 62

T3 - Journal of Labelled Compounds and Radiopharmaceuticals

SP - S303-S303

BT - Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019

Y2 - 26 May 2019 through 31 May 2019

ER -

Burgoyne A, Ooms M , Cardinaels T , Elema D. Tb-161 Purification by high performance ion chromatography (HPIC) from irradiated Gd-160: Poster Category: Radiochemistry ‐ Radiometals. In Supplement: The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) Beijing, China, 26–31 May 2019. Vol. 62. 2019. p. S303-S303. (Journal of Labelled Compounds and Radiopharmaceuticals). doi: 10.1002/jlcr.3725