The effects of a fractionated gamma irradiation on life shortening and diseases incidence in BALB/c mice

J. R. Maisin; A. Wambersie; G. B. Gerber; G. Mattelin; M. Lambiet-Collier; J. Gueulette

doi:10.2307/3575970

The effects of a fractionated gamma irradiation on life shortening and diseases incidence in BALB/c mice

J. R. Maisin, A. Wambersie, G. B. Gerber, G. Mattelin, M. Lambiet-Collier, J. Gueulette

Research output › peer-review

Abstract

BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of ¹³⁷Cs γ rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk analysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 ±3.1 days/Gy) as for single (46.2 ±4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.

Original language	English
Pages (from-to)	359-373
Number of pages	15
Journal	Radiation Research
Volume	94
Issue number	2
DOIs	https://doi.org/10.2307/3575970
State	Published - 1983

ASJC Scopus subject areas

Biophysics
Radiation
Radiology Nuclear Medicine and imaging

Access to Document

10.2307/3575970

Cite this

@article{d43bb4e53c624a8c8ffaf2cc4b7fa1d4,

title = "The effects of a fractionated gamma irradiation on life shortening and diseases incidence in BALB/c mice",

abstract = "BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of 137Cs γ rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk analysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 ±3.1 days/Gy) as for single (46.2 ±4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.",

author = "Maisin, {J. R.} and A. Wambersie and Gerber, {G. B.} and G. Mattelin and M. Lambiet-Collier and J. Gueulette",

year = "1983",

doi = "10.2307/3575970",

language = "English",

volume = "94",

pages = "359--373",

journal = "Radiation Research",

issn = "0033-7587",

publisher = "Radiation Research Society",

number = "2",

}

TY - JOUR

T1 - The effects of a fractionated gamma irradiation on life shortening and diseases incidence in BALB/c mice

AU - Maisin, J. R.

AU - Wambersie, A.

AU - Gerber, G. B.

AU - Mattelin, G.

AU - Lambiet-Collier, M.

AU - Gueulette, J.

PY - 1983

Y1 - 1983

N2 - BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of 137Cs γ rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk analysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 ±3.1 days/Gy) as for single (46.2 ±4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.

AB - BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of 137Cs γ rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk analysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 ±3.1 days/Gy) as for single (46.2 ±4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.

UR - http://www.scopus.com/inward/record.url?scp=0020607550&partnerID=8YFLogxK

U2 - 10.2307/3575970

DO - 10.2307/3575970

M3 - Article

AN - SCOPUS:0020607550

SN - 0033-7587

VL - 94

SP - 359

EP - 373

JO - Radiation Research

JF - Radiation Research

IS - 2

ER -