Abstract
The release of platelets into the circulation is preceded by considerable morphologic change of the parent megakaryocyte. The cell extends cytoplasmic processes into the venous sinusoids, which develop constrictions at intervals, revealing putative platelets. The pattern of cytoskeletal distribution changes during the spreading of megakaryocytes in vitro. In this review, an attempt was made to summarize the data of the literature concerning the changes in the cytoskeletal pattern of megakaryocytes during their spreading and platelet formation.
Original language | English |
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Pages (from-to) | 17-19 |
Number of pages | 3 |
Journal | Blood reviews |
Volume | 10 |
Issue number | 1 |
DOIs | |
State | Published - 1996 |
Funding
This work was supported by a grant from the Fonds National de la Recherche Scientifique-T&vie (Grant no 7.4549.93). The author would like to thank Professor M. Symann, Dr C. Chatelain and Mr B. Chatelain for their continued support.
Funders | Funder number |
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Not added | 7.4549.93 |
ASJC Scopus subject areas
- Hematology
- Oncology