The radiosensitivities of lymphocytes from pig, sheep, goat and cow

A. Leonard, G. B. Gerber, D. G. Papworth, G. Decat, E. D. Leonard, Gh Deknudt

    Research outputpeer-review

    Abstract

    Dose-effect curves for X-irradiation in vitro were determined on cultured blood lymphocytes of four mammalian speciec - cow, goat, sheep and pig - having approximately the same number of chromosome arms, the same nuclear volume and the same DNA content. The data from cow, but not those from the other species, exhibited significant inhomogeneity between the experiments. On inspection the numerical yields appear not to differ greatly in the lower dose range. Evaluation of the parameters according to the quadratic law and the power law, however, demonstrate significant differences. Pig differs from the other species regardless of which presentation is chosen. For the power law a significant difference is also found between goat and sheep.

    Original languageEnglish
    Pages (from-to)319-332
    Number of pages14
    JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
    Volume36
    Issue number3
    DOIs
    StatePublished - Sep 1976

    ASJC Scopus subject areas

    • Molecular Biology
    • Genetics
    • Health, Toxicology and Mutagenesis

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